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Gasification of biomass by partial oxidation produces both syn-gas with high hydrogen content and explore energy of renewable sources. The objective of this work was to develop computer models of pilot reactor unit operated partial oxidation of rape meal/mineral oil suspension. The models were developed in process simulator ASPEN Plus based both on Gibbs free energy minimization and reaction kinetic approach. Alternative biomass characterizations were used: analogy with coal composition and representative compounds of biopolymer structure. Flow characteristic of gasification reactor was tested by CFD method in COMSOL Multiphysic. Simulated results were compared with pilot plant experiments with successful agreement.